Rattler Antivenin benefits both veterinarians and pet owners alike while maintaining a beneficial price point.
Three-year shelf life. Stored frozen, Rattler Antivenin is good for three years from manufacture date.
Ready to use in five minutes. Thaw using a warm water bath; does NOT require reconstitution or dilution.
Cross-protective. Shown to be effective against envenomation in canine and equine due to North American Crotalidae. Crotalidae refers to the Crotalinae subfamily (commonly named ‘Pit Vipers’) and includes cottonmouths/water moccasins, copperheads, and rattlesnakes.
Neutralizes venom. Packaged in a “one-and-done” IV pouch. Combining research from both in the field and in the lab, Rattler Antivenin is potent enough to treat the typical envenomation case with a single dose.
Neutralizes Mohave Venom A. The only licensed product that includes specific antibodies proven to neutralize venom from Mohave Rattlesnake Type A.
Safe to use. May be used alongside typical post-snake bite therapies.
Safe with vaccine. Safe and compatible for use in previously vaccinated patients. Rattler Antivenin shares no common proteins with the industry’s most widely used rattlesnake vaccine.
Made in the USA. Manufactured and distributed by Mg Biologics and proudly made in Ames, Iowa.
Available direct from Mg Biologics. Delivered in two days or less. Same day shipping for orders placed by 2:00PM CST (M-F in most cases).
Clinical evaluations of Rattler Antivenin in dogs and horses within 24 hours of snake bite demonstrated to significantly: Neutralize venom, decrease swelling, reduce and/or eliminate pain, decrease temperature and reduce the overall hospitalization time.
Rattler Antivenin has undergone rigorous studies and was proven to be safe and efficacious, meeting all of the stringent requirements to attain USDA licensure. In continuing this standard, each serial is passed through a series of strict quality assurance tests to ensure the highest quality product is being provided to the industry. Below are a few study summaries highlighting the quality and efficacy of Rattler Antivenin.
1200 doses. Less than 1% reported adverse event. Rattler Antivenin’s high safety statistics are highlighted by the fact that out of 1200 doses distributed in the field, only 0.76% reported an adverse event in canine cases and zero reported adverse equine cases. There were also no reports of delayed hypersensitivity (serum sickness), volume overload, or recurrence (returning symptoms due to incomplete venom neutralization).
Clinical trials, a detailed evaluation. Clinical evaluations were performed at 17 veterinary clinics on 132 envenomated dogs and 34 envenomated horses presenting with mild to severe symptoms of envenomation. Of these patients, 100% of horses, and 93% of dogs survived envenomation following snake bites when treated to effect with Rattler Antivenin (the remaining canine cases succumbed to complications due to envenomation).
In-vivo neutralization test. A goal of Mg Biologics is to provide a product that can be used as a single treatment in the typical envenomation. One of the research methods involved venom neutralization in a mouse model. Lethality and efficacy (LD50/ED50) studies in mice using Rattler Antivenin were performed to determine efficacy of venom neutralization in a live model. The ED50 was robust, successfully testing the product against five times the LD50, demonstrating that Rattler Antivenin effectively neutralized venom up to five times the dose of venom that would have killed 50% of the mice. By maintaining a hearty efficacy, we are changing the paradigm where multiple doses may no longer be needed to treat the typical snake bite.
*Published data pending peer review
A horse, labrador, and chihuahua each receive the entire 50ml treatment.
Do I use the whole thing, even on a Chihuahua?
Yes. Rattler Antivenin has been specifically formulated to neutralize the typical amount of venom released during a bite. It is crucial to administer the entire 50ml treatment.
As body size gets smaller, the amount of venom circulating proportional to the body increases. Every patient (no matter the size) should receive at least one full 50ml treatment of Rattler Antivenin for optimum neutralization.
That’s a lot of fluid for a Chihuahua, how fast do I administer?
Administer to effect intravenously using a filtered IV administration set over a 20-60 minute period (standard rate of infusion). Small animals may require a slower administration time, with short breaks, to ensure the entire treatment is administered without risking volume overload. Please use professional judgment.
When do I use more than one treatment?
As you, the veterinarian, know, each case can be different. There may be times when using more than one treatment is right for your patient. Multiple doses are safe to administer.
Circumstances that may merit a second treatment include:
Multiple bites / Bites near airways / Very small patients / If bite happened more than 2 hours prior to administration / If no physical or clinical progress has been made 4-8 hours since first treatment (clotting times may be a good indicator of this progress).
Dosage and Administration: Administer to effect intravenously using a filtered IV set over a 20-60 minute period. Warm to body temperature using a warm water bath prior to administration. One to two 50ml doses will be sufficient in most cases regardless of body size (equine, small canine, large canine). Additional doses may be necessary on a case-by-case basis. Factors to consider include the severity of envenomation, type and size of snake, and size of patient (the smaller the body of the victim, the more the venom to blood volume ratio increases).Administer Rattler Antivenin as is, without reconstitution or dilution. Do not mix this product with other fluids. As with any antivenin, additional fluids and supplemental therapies can be used. Rattler Antivenin has been administered in conjunction with, prior to, or immediately after other fluids and no direct risk or contraindication to the patient has been reported. Use professional judgment.
The use of corticosteroids is controversial. Use professional discretion.
Restricted to use by or under the direction of a licensed veterinarian.